Victor Ambros and Gary Ruvkun get awarded the Nobel Prize for Medicine 2024 for discovery of microRNA and its role in post-transcriptional gene regulation.
The 5th SFB RNA DECO annual retreat took place in Vienna at the Division of Cell and Developmental Biology, on 12th and 13th of September providing an overview of current research in the field of RNA especially chemical modifications of RNA.
Nobel Laureate Tom Cech describes importance of RNA and RNA modifications in a New York times article.
Maria Kompatscher from Matthias Erlacher’s lab successfully defended her Ph.D. thesis on “Effects of tRNA sequence and modifications on various aspects of translation”.
The mid-term meeting of RNA DECO was organized at the CCB in Innsbruck February 1st and 2nd.
Laurin Flemmich from Ronald Micura’s lab successfully defended his Ph.D. thesis on “From Riboswitches to Ribozymes: Unveiling the Catalytic Potential of non-coding RNA”.
The application for extension of the research network RNA-DECO was succsessfully funded for the coming four years, 2024-2028.
Katalin Karikó and Drew Weissmann get awarded the Nobel Prize for Medicine 2023 for their discoveries showing that RNA modifications introduced into RNA-based vaccines can successfully prevent activation of the innate immune system against the RNA itself.
Branimir Ayvazov from Javier Martinez´s lab successfully completed an internship on “Characterization of the ANGEL2-PRMT1 protein complex”.
Renata Kleinova from Michael Jantsch’s lab successfully defended her Ph.D. thesis on “The ADAR1 editome reveals drivers of editingspecificity for ADAR1-isoforms”.
Ramesh PILLAI gave a talk at the 17th Microsymposium on RNA Biology Vienna.
The 4th SFB RNA DECO annual retreat took place at Schlosshotel Mondsee in Salzburg on 27th and 28th of April providing an overview of current research in the field of RNA especially chemical modifications of RNA.
The VIENNA RNA CONFERENCE: MODIFICATION AND PROCESSING took place from the 26th to the 29th of OCTOBER 2022 in Vienna.
Valentina Stuchlik from Elisa Vilardo’s lab successfully defended her master thesis on “Investigating the role of Archease on tRNA methylation by NSUN2 in mammals”.
Zsuzsanna Pinter from Matthias Schaefer’s lab successfully defended her diploma thesis on “Quantitative Bestimmung von nicht-kodierenden RNAs in den Spermatozoen der Maus-eine explorative experimentelle Studie”.
The 3rd SFB RNA DECO annual retreat took place at at Vienna Biocenter in Vienna, on the 23rd and 24th of June 2022 providing an overview of current research in the field of RNA especially chemical modifications of RNA.
Maximilian Kohl from Matthias Erlacher’s lab successfully defended his master thesis on “Translation initiation at ambiguous start sites: setting the right frame”.
Nikolaus Beer from Stefan Ameres’s lab successfully defended his master thesis on “An inducible dual-guide CRISPR/Cas9 approach resolves the cellular assembly and functions of mammalian RNA exosome subunits”.
Mortiz Leitner from Javier Martinez´s lab successfully defended his master thesis on “The post-translational fate of human ANGEL2”.
Moritz Staltner from Stefan Ameres’s lab successfully defended his Ph.D. thesis on “Massive parallel mRNA tethering by ORF-trap examines the post-transcriptional gene regulatory proteome in mouse embryonic stem cells”
An in person meeting as part of the SFB RNA Deco Seminar Series was organized at 11th March 2022 in Innsbruck.
Rozi Mkrtchyan from Javier Martinez´s lab successfully defended his bachelor thesis on “PYROXD1, a novel oxido-reductase that protects the tRNA ligase from oxidation”.
An in person meeting as part of the SFB RNA Deco Seminar Series was organized at 14th January 2022 in Vienna.
Melanie Brunner from Alexandra Lusser´s lab successfully defended her master thesis on “Metabolic labeling of mRNA using different prodrugs”.
Bugra Yaman from Javier Martinez´s lab successfully defended her master thesis on “Gene expression analyses of zebrafish angel proteins”.
Laura Borac from Matthias Schaefer’s lab successfully defended her master thesis on “Establishment of a fluorescence in situ hybridization-based methodology for the visualization of specific tRNA-derived fragments”.
The 2nd SFB RNA DECO annual retreat took place at Innsbruck, Tyrol from the 17th to 19th of September 2021 providing an overview of current research in the field of RNA especially chemical modifications of RNA.
Gregor Diensthuber from Michael Jantsch’s lab successfully defended his master thesis on “Deciphering the crosstalk between A-to-I editing and m6A”.
Thomas Spicher from Ivo Hofacker’s lab successfully defended his master thesis on “Computational estimation of energy parameters for RNA folding“.
Susanne Böhler from Alexandra Lusser´s lab successfully defended her bachelor thesis on “Characterization of Archease knock-down ESCs”.
Aleksej Drino from Matthias Schaefer’s lab successfully defended his Ph.D. thesis on “Biochemical identification of protein-tRNA fragment interactions”.
The 1st SFB RNA DECO annual retreat took place at Schlosshotel Mondsee in Salzburg on the 7th & 8th of September providing an overview of current research in the field of RNA especially chemical modifications of RNA.
The Austrian Science Fund (FWF) is establishing a new specialist research area called RNA-DECO. Over the next four years, total funding of over €4 million will be provided to fund a total of 12 research groups, who will study the chemical modification of ribonucleic acid (RNA). Five of these research groups (Walter Rossmanith, Matthias Schäfer, Elisa Vilardo, Javier Martinez, Michael Jantsch) are based at MedUni Vienna. Overall project leader is Michael Jantsch, Head of MedUni Vienna’s Centre for Anatomy and Cell Biology.
Sabrina Summer from Walter Rossmanith’s lab successfully defended her Ph.D. thesis on “YBEY is an essential biogenesis factor for mitochondrial ribosomes”.
Matthias Villunger from Alexandra Lusser´s lab successfully defended his bachelor thesis on “Characterization of RNA methyltransferase knock-out cells”.
Forscherinnen und Forscher der Innsbrucker Universitäten haben ein vor drei Jahren entwickeltes Verfahren zur Analyse von Boten-RNA in der Zelle gemeinsam weiterentwickelt. In der Fachzeitschrift Angewandte Chemie International Edition demonstrieren sie, wie mit einem zusätzlichen chemischen Label Produktion und Abbau von Boten-RNA detailliert analysiert werden können.